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Overview of the unmet needs in GvHD, and an introduction to ECP therapy

By Devon Else

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Jan 19, 2026

Learning objective: After reading this article, learners will be able to describe the current unmet needs and challenges in GvHD and explain the rationale for ECP therapy in GvHD.


Do you know... Which of the following is not true regarding the rationale for use of ECP in GvHD?

Despite the use of prophylactic measures, graft-versus-host disease (GvHD) remains an ongoing complication for patients following allogeneic hematopoietic stem cell transplantation (allo-HSCT).

In the first chapter of this e-learning module, we describe the ongoing unmet needs and challenges in the management of both acute and chronic GvHD, provide an overview of the proposed mechanism of action of extracorporeal photopheresis (ECP) therapy, and explain the rationale for its use in the treatment of GvHD.

Click through the slides below to learn more.

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The second chapter of this e-learning module will be published shortly.

 

This educational resource is independently supported by Therakos. All content was developed by SES in collaboration with an expert steering committee. Funders were allowed no influence on the content of this resource. 

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The content was clear and easy to understand

The content addressed the learning objectives

The content was relevant to my practice

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Your opinion matters

What do you see as the main advantage of including ECP + Rux as an upfront combination?