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Chronic graft-versus-host disease
Chronic graft-versus-host disease
Chronic graft-versus-host disease (cGvHD) is a serious and life-threatening complication of allogeneic hematopoietic stem cell transplantation. It is caused by a chronic reaction of donor immune cells against host tissues and can develop at any time after transplantation. Multiple organs are usually involved, in particular the oral mucosa and gastrointestinal tract, the skin, and the liver.