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Drug updates

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Important announcement
🚨NEWS🚨 @US_FDA approves once-daily, extended-release tablet formulation of ruxolitinib for patients aged ≥12 years with steroid-refractory #aGvHD or #cGvHD after 1–2 prior lines of systemic therapy. Read more: https://bit.ly/4dlHDBv
Important announcement
@TGAGovAU approves axatilimab, a first-in-class anti-CSF-1R antibody, under priority review in Australia for adult and pediatric patients aged ≥6 years (≥40 kg) with #cGvHD after ≥2 prior systemic therapies; based on phase II AGAVE-201 data. Read more: prn.to/3Pph5WR
Important announcement
@US_FDA approves the investigational new drug application for a phase Ib/IIa trial of CK0802, an allogeneic CAR-engineered NK cell therapy, for the treatment of patients with SR-GvHD. Read more: prn.to/3Pk1AiY
Important announcement
@US_FDA grants RMAT designation to Orca-Q, an investigational allogeneic T-cell therapy, for the treatment of high-risk hematologic malignancies; based on promising OS, #GvHD, and NRM data from an ongoing phase I trial. Read more: bit.ly/4eQcU0r