Strategies to improve hematopoietic stem cell engraftment and reduce GvHD

Engraftment of transplanted hematopoietic stem cells (HSCs) is essential for effective long-term hematopoiesis and an...

What is the impact of chronic GvHD on first late effects in transplant survivors?

During the 2021 TCT Meetings Digital Experience, the GvHD Hub spoke to Catherine J. Lee, The University of Utah, Salt...

De-escalation of posttransplant cyclophosphamide in preventing acute graft-versus-host disease

Hematopoietic cell transplantation (HCT) provides a valid option to cure or manage blood cancers. One of...

A phase III trial of omidubicel versus standard umbilical cord blood for improved stem cell engraftment

Advantages of allogenic transplantation with umbilical cord blood (UCB) stem cells over bone...

How can we use microbial-derived metabolites to prevent GvHD?

During the 47th Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT), the GvHD Hub spoke to Erik Thiele...

NCCN COVID-19 vaccination recommendations for patients with hematologic malignancies

Patients with cancer are at high risk of COVID-19-associated complications and, accordingly, the preliminary...

Ruxolitinib fails to provide clinical benefit in patients with COVID-19-related cytokine storm

he efficacy and safety of adding ruxolitinib to standard of care (SoC) for patients with...

Use of ruxolitinib in patients with severe COVID-19

A summary of the prospective observational study by the RUXO-COVID Study Group assessing response to ruxolitinib treatment in 34 patients with...

How can patient-reported QoL change our view on unmet needs in GvHD?

During the 47th Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT), the GvHD Hub spoke to Nada...

Strategies to improve hematopoietic stem cell engraftment and reduce GvHD

Engraftment of transplanted hematopoietic stem cells (HSCs) is essential for effective long-term hematopoiesis and an...

How can CMV infection increase the risk of chronic GvHD?

During the 47th Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT), the GvHD Hub spoke to Katrine Kielsen,...

Editorial theme | Using a stem cell source as prophylaxis for cGvHD

Peripheral blood stem cells (PBSC) have become the predominant source of cells for hematopoietic stem cell transplantation (HSCT)...