Updated results from a phase Ib and phase I/II trial of Orca-T

During the 27th Congress of the European Hematology Association (EHA2022), Caspian Oliai presented updated results of a multicenter phase...

Efficacy of early repeated infusion of MSCs in GvHD prophylaxis after haplo-HSCT

During the European Hematology Association (EHA) 2022 Congress, Huang presented results of their trial...

How to optimize donor selection for allogeneic transplant?

Nagler begins by comparing leukemia-free and relapse-free survival with different donor types, including sibling, unrelated, mismatched, and...

Non-restrictive diet post-HSCT: Preliminary analysis of phase III prospective trial data presented at EHA2022

Despite the widespread use of restrictive diets post-hematopoietic stem cell...

The safety and efficacy of low-dose interleukin-2 for the treatment of SR-cGvHD

Here, we discuss the combined results of five phase I or II clinical trials (NCT00529035, NCT01366092, NCT01937468,...

How should novel agents be used in the current treatment pathways for GvHD?

During the GvHD Hub Steering Committee meeting on April 5, 2022, key opinion leaders met to debate the question of how novel...

Abatacept as a novel agent for the treatment of steroid-refractory cGvHD: A phase II trial

The results of a phase II clinical trial of abatacept for steroid-refractory chronic graft-versus-host...

How would you treat aGvHD in your clinic (an EU perspective)?

During the 2022 Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR (Tandem Meetings), the GvHD Hub was pleased to speak to...

Findings from the prospective iMAGINE trial of ibrutinib in pediatric patients with chronic GvHD

Chronic graft-versus-host disease (cGvHD) is a significant cause of mortality and morbidity after...

Editorial theme: T-cell depletion strategies to reduce incidence of GvHD in pediatric HSCT recipients

The current educational theme on the GvHD Hub explores the treatment of pediatric...

How does GvHD affect outcomes for pediatric patients undergoing allo-SCT for ALL?

During the 48th Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT), the ALL Hub spoke...

Editorial theme: Genetic predisposition and endoscopic diagnosis of aGvHD in pediatric patients

In this article, we summarize two publications; one on the genetic susceptibility of pediatric patients...