Editorial theme | Latest updates on cGvHD treatment

First-line treatment for chronic graft-versus-host disease (cGvHD), which consists of steroids, has not changed much over the last three decades. In...

Strategies to improve hematopoietic stem cell engraftment and reduce GvHD

Engraftment of transplanted hematopoietic stem cells (HSCs) is essential for effective long-term hematopoiesis and an...

What is the impact of chronic GvHD on first late effects in transplant survivors?

During the 2021 TCT Meetings Digital Experience, the GvHD Hub spoke to Catherine J. Lee, The University of Utah, Salt...

De-escalation of posttransplant cyclophosphamide in preventing acute graft-versus-host disease

Hematopoietic cell transplantation (HCT) provides a valid option to cure or manage blood cancers. One of...

COVID-19 vaccination for hematopoietic stem cell transplant patients

The SARS-CoV-2 pandemic has changed the world over the last year and impacted almost every part of our lives. In particular,...

How can we use microbial-derived metabolites to prevent GvHD?

During the 47th Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT), the GvHD Hub spoke to Erik Thiele...

NCCN COVID-19 vaccination recommendations for patients with hematologic malignancies

Patients with cancer are at high risk of COVID-19-associated complications and, accordingly, the preliminary...

Ruxolitinib fails to provide clinical benefit in patients with COVID-19-related cytokine storm

he efficacy and safety of adding ruxolitinib to standard of care (SoC) for patients with...

Combination of myeloablative conditioning with regulatory and conventional T-cell immunotherapy for AML

The most effective treatment for high-risk acute myeloid leukemia (AML) is allogeneic...

A phase II trial of PTCy versus ATG for GvHD prophylaxis after RIC regimen allo-HCT

The development of graft-versus-host disease (GvHD) can significantly impact the outcomes of patients who have...

COVID-19 vaccination for hematopoietic stem cell transplant patients

The SARS-CoV-2 pandemic has changed the world over the last year and impacted almost every part of our lives. In particular,...

Impact of viral infection on post-HSCT mixed T-cell chimerism in pediatric patients receiving alemtuzumab conditioning

Alemtuzumab conditioning for allogeneic hematopoietic stem cell transplantation...