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GvHD prophylaxis: novel strategies and future directions

Dec 13, 2023
Learning objective: After reading this article, learners will be able to describe the latest data relating to GvHD prophylaxis and their impact on clinical practice.

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During the GvHD Hub Steering Committee Meeting in October 2023, key opinion leaders met to discuss GvHD prophylaxis, including novel strategies and future directions. The recorded discussion was chaired by Professor Mohamad Mohty and featured Mutlu Arat, Ali Bazarbachi, Yi-Bin Chen, Amin Alousi, Arnon Nagler, Attilio Olivieri, and Robert Zeiser.


GvHD prophylaxis: novel strategies and future directions

The steering committee discussed how there is a need for the results from comparative trials in order to inform prophylaxis choices in clinical practice. The experts considered regimens involving combinations of post-transplant cyclophosphamide, tacrolimus, ruxolitinib, and mycophenolate mofetil, and how combinations could be optimized in immunosuppressed patients. The experts also discussed which prophylactic regimens they would use in cases of comorbidities.


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