Symposium | Panel discussion: Shifting the treatment paradigm in cGvHD

During the 8th International Chronic Graft-versus-Host Disease Symposium, the GvHD Hub held a live symposium on May 22, 2026, titled Evolving treatment strategies in SR‑cGvHD: Optimizing patient selection across current and emerging therapies. 

The symposium closed with a panel discussion that included questions from the audience. The panelists, Zinaida Perić, Daniel Wolff, and Corey Cutler, shared their perspectives on several key topics, including:

• Applying insights from the treatment of other fibrotic diseases (e.g., myelofibrosis) to chronic graft-versus-host disease (cGvHD), including whether inflammation and fibrosis can be managed using similar therapeutic approaches.
• The role of combination therapy in cGvHD, including the importance of balancing efficacy and toxicity, and when to add versus switch therapies based on treatment response.
• Approaches to treating specific manifestations of cGvHD, taking into account regulatory labeling and patient- and treatment-related factors.
• Strategies for managing late-onset, rapidly progressing sclerotic cGvHD that is refractory to corticosteroids.

This educational resource is independently supported by Sanofi. All content is developed by the faculty in collaboration with SES. Funders are allowed no influence.