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Chemokine receptor antagonists

Chemokine receptor antagonists

Chemokine receptor antagonists are small molecules that selectively bind to a specific chemokine receptor on tumor or stromal cells. The binding leads to the inhibition of the receptor’s signaling pathway, which may lead to inhibition of various functions, such as immune cell recruitment and activation, stem cell homing, angiogenesis, cancer cell proliferation, and metastasis.

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