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2024-07-23T17:50:17.000Z

Symposium | Early intervention and use of ECP combinations in cGvHD

Jul 23, 2024
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Learning objective: After reading this article, learners will be able to state when, why, and how to combine ECP with other therapies, such as immunosuppressive agents, for cGvHD treatment.

Test your knowledge! Take our quick quiz before and after you read this article to find out if you improved your knowledge. Results help us to improve content and continually provide open-access education.

On April 14, 2024, the GvHD Hub held a symposium at the 50th European Society for Bone and Marrow Transplantation (EBMT) Annual Meeting on the role of extracorporeal photopheresis (ECP) in the management of chronic graft-versus-host disease (cGvHD).

Here, we share the presentation by Florent Malard, Hôpital Saint-Antoine and Sorbonne Université, Paris, FR, that explored early intervention and ECP-based combinations. Mallard covered use of ECP first-line, as well as ECP combinations in patients with steroid-refractory and steroid-dependent cGvHD, including recent approvals and findings from clinical trials.

Listen to this presentation as a podcast here:

Symposium | Early intervention and use of ECP combinations in cGvHD

Q&A session

This symposium closed with a panel Q&A session with live audience participation, where our panelists shared their thoughts on how ECP can affect lymphocyte count during and after treatment.

 

Symposium | Q&A | How ECP can affect lymphocyte count during and after treatment?

This independent educational activity was supported by Mallinckrodt Pharmaceuticals. All content was developed independently by the faculty. The funder was allowed no influence on the content of this activity.


  1. Flower MED, Apperley JF, van Besien K, et al. A multicenter prospective phase 2 randomized study of extracorporeal photopheresis for treatment of chronic graft-versus-host disease. Blood. 2008;112(7):2667-74. DOI: 10.1182/blood-2008-03-141481
  2. Jagasia M, Alyea EP, Ahmed S, et al. Optimizing Post-Allogeneic Hematopoietic Cell Transplant Outcomes for Lymphoma Using Ibrutinib: Early Safety Results of a Multicenter Study. Biol Blood Marrow Transplant. 2019;25(3):(Suppl_28-29). DOI: https://doi.org/10.1016/j.bbmt.2018.12.819 

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