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Symposium | A brief overview and history of ECP

Featured:

Mohamad MohtyMohamad Mohty

Jul 12, 2024

Learning objective: After watching this video, learners will be able to state when to use ECP in patients with cGvHD.


Test your knowledge! Take our quick quiz before and after you read this article to find out if you improved your knowledge. Results help us to improve content and continually provide open-access education.

Question 1 of 1

According to a study with adult patients undergoing their first allo-SCT in France by Malard et al., the cumulative incidence of extensive cGvHD at 2 years remained stable between 1983 and 2000. How did the incidence change between 2001 and 2010?

A

B

C

D

Video series

On April 14, 2024, the GvHD Hub held a symposium at the 50th European Society for Bone and Marrow Transplantation (EBMT) Annual Meeting on the role of extracorporeal photopheresis (ECP) in the management of chronic graft-versus-host disease (cGvHD).  

Here, we share the presentation by Mohamad Mohty, Hôpital Saint-Antoine and Sorbonne Université, Paris, FR, which explored a brief history of ECP, outlined the allogeneic hematopoietic stem cell transplantation (Figure 1) and ECP procedures (Figure 2), and also included two cGvHD patient case studies. 


Figure 1. The allo-HSCT procedure*

aGvHD, acute graft-versus-host disease; allo-HSCT, allogeneic hematopoietic stem cell transplantation; cGvHD, chronic graft-versus-host disease; CMV, cytomegalovirus; GvHD, graft-versus-host disease. 

*Adapted from Mohty, et al.2 Created with Biorender.com.

 

Figure 2. What is ECP?

ECP, extracorporeal photopheresis; GvHD, graft-versus-host disease; UVA, ultraviolet A. 

*Adapted from Knobler R, et al.3 Created with Biorender.com 


Q&A session 

This symposium closed with a panel Q&A session with live audience participation, where our panelists shared their perspectives on the impact of ECP on the GvHD treatment landscape and the importance of early intervention in GvHD treatment. 


Symposium | Q&A | Impact of ECP on the GvHD treatment landscape

 

This independent educational activity was supported by Mallinckrodt Pharmaceuticals. All content was developed independently by the faculty. The funder was allowed no influence on the content of this activity. 

References

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