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Real-world effectiveness of MSC-FFM in ruxolitinib-refractory aGvHD

By Haimanti Mandal

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Feb 7, 2025

Learning objective: After reading this article, learners will be able to cite real-world effectiveness of salvage treatment with mesenchymal stromal cells in patients with ruxolitinib-refractory aGvHD.


GvHD Hub spotlight: Real-world effectiveness of MSC-FFM in RR-aGvHD

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Given the poor prognosis of patients with steroid-refractory acute graft-versus-host disease (aGvHD), new treatment options are needed. Bonig et al. from Goethe University, Frankfurt, Germany; Institute Frankfurt, Frankfurt, Germany; University of Washington, Seattle, WA, USA; published an article in the Journal of Translational Medicine discussing the effectiveness and tolerability of salvage treatment with the allogeneic mesenchymal stromal cell-Frankfurt am Main (MSC-FFM) in heavily pre-treated patients with ruxolitinib-refractory aGvHD in real-world clinical settings.

This educational resource is independently supported by Medac. All content was developed by SES in collaboration with an expert steering committee; funders were allowed no influence on the content of this resource. 

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