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REACH3 study: Should ruxolitinib become SoC for steroid-dependent or refractory chronic GvHD?

Jan 11, 2021
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During the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, the GvHD Hub spoke to Robert Zeiser, Medical Center – University of Freiburg, Freiburg, DE. We asked, Should ruxolitinib become standard of care for steroid-dependent or refractory chronic GvHD?

The standard first-line treatment for chronic GvHD includes systemic corticosteroids; however, patients who become steroid-dependent or refractory require additional treatments. Here, Zeiser reports the findings from the phase III REACH3 study on ruxolitinib versus best available therapy in patients with steroid-dependent or refractory chronic GvHD.

Read a summary of the phase III REACH3 study, here.

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