The GvHD Hub uses cookies on this website. They help us give you the best online experience. By continuing to use our website without changing your cookie settings, you agree to our use of cookies in accordance with our updated Cookie Policy

Is the composition of gut fungal microbiota a predictor of mortality after allo-transplantation?

Dec 12, 2019

The GvHD Hub are proud to present expert interviews directly from the 61st American Society of Hematology (ASH) meeting in Orlando, US. This interview with Florent Malard, Saint-Antoine Hospital, Paris, FR, was based on the question: Is the composition of gut fungal microbiota a predictor of mortality after allogeneic transplantation?

Dr Malard discusses the results of a study, presented during the ASH meeting, which found patients undergoing transplant had a low fungal microbiota diversity at day 0. This lack of diversity did not have an impact on outcome, unlike the bacteria microbiota. However, a high presence of Candida albicans at day 0 was associated with lower overall survival and GvHD-free disease-free survival. He concludes that moving forward, it will be important to consider how we integrate this new data into improvements in patient outcome.

Is the composition of gut fungal microbiota a predictor of mortality after allo-transplantation?