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During the EHA 2022 Congress, the GvHD Hub was pleased to speak to Robert Zeiser, Medical Center – University of Freiburg, Freiburg, DE. We asked, What is the role of human beta-defensin-2 (HBD-2) in modulation of the microbiome and acute GvHD (aGvHD)?
What is the role of human beta-defensin-2 in modulation of the microbiome and aGvHD?
Zeiser begins by discussing the high frequency of patients who develop aGvHD despite receiving prophylaxis. Zeiser also talks about the antimicrobial, immunosuppressive, and immunomodulatory functions of HBD-2, and how it can affect GvHD development and severity.
Updated results from a phase Ib and phase I/II trial of Orca-T
During the 27th Congress of the European Hematology Association (EHA2022), Caspian Oliai presented updated results of a multicenter phase Ib trial (NCT04013685) and single-center phase...
Unusual manifestations of acute GvHD
During the 46th Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT), the GvHD Hub spoke to Robert Zeiser, Medical Center – University of Freiburg, Freiburg, DE, about unusual...
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