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During the 64th American Society of Hematology (ASH) Annual Meeting and Exposition, the GvHD Hub was pleased to speak to Robert Zeiser, University of Freiburg, Freiburg, DE. We asked, What is the latest update on the GRAVITAS-309 trial?
What is the latest update on the GRAVITAS-309 trial?
In this interview, Zeiser presents the initial results from ASH abstract #771: ‘Itacitinib and Corticosteroids As initial Treatment for Chronic Graft-Versus-Host Disease: Phase 1/2 Results from Gravtias-309.’
Firstly, Zeiser discusses how the anti-inflammatory properties of itacitinib as a JAK 1 inhibitor may be beneficial in chronic GvHD. He goes on to outline the overall efficacy and safety of itacitinib in combination with corticosteroids.
ASH 2022 abstracts: What’s hot in GvHD?
To help navigate the exciting content being presented at ASH 2022, the GvHD Hub Steering Committee have provided their recommendations for the top abstracts to look out for in GvHD.
Editorial theme | Latest updates on cGvHD treatment
First-line treatment for chronic graft-versus-host disease (cGvHD), which consists of steroids, has not changed much over the last three decades. In the case of severe cGvHD, another...
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