All content on this site is intended for healthcare professionals only. By acknowledging this message and accessing the information on this website you are confirming that you are a Healthcare Professional.

The GvHD Hub uses cookies on this website. They help us give you the best online experience. By continuing to use our website without changing your cookie settings, you agree to our use of cookies in accordance with our updated Cookie Policy

Introducing

Now you can personalise
your GvHD Hub experience!

Bookmark content to read later

Select your specific areas of interest

View content recommended for you

Find out more
  TRANSLATE

The GvHD Hub website uses a third-party service provided by Google that dynamically translates web content. Translations are machine generated, so may not be an exact or complete translation, and the GvHD Hub cannot guarantee the accuracy of translated content. The GvHD Hub and its employees will not be liable for any direct, indirect, or consequential damages (even if foreseeable) resulting from use of the Google Translate feature. For further support with Google Translate, visit Google Translate Help.

Steering CommitteeAbout UsNewsletterContact
Visit:
ALL Hub

ALL Hub

AML Hub

AML Hub

Lupus Hub

Lupus Hub

Lymphoma Hub

Lymphoma Hub

MPN Hub

MPN Hub

Multiple Myeloma

Multiple Myeloma Hub

PsOPsA Hub

PsOPsA Hub

LOADING
You're logged in! Click here any time to manage your account or log out.
LOADING
You're logged in! Click here any time to manage your account or log out.
Steering CommitteeAbout UsNewsletterContact
TypesTherapeuticsCongressesTrialsExpert OpinionsDRUG UPDATES
2022-12-14T16:03:20.000Z

What is the latest update on the GRAVITAS-309 trial?

By Alice Hyde, Becky Gribbell, Erika Roa, Jennifer Higgins
Featured
Robert Zeiser
Dec 14, 2022
Share:
Learning objective: After reading this article, learners will be able to cite a new clinical development in chronic GvHD.

Bookmark this article

During the 64th American Society of Hematology (ASH) Annual Meeting and Exposition, the GvHD Hub was pleased to speak to Robert Zeiser, University of Freiburg, Freiburg, DE. We asked, What is the latest update on the GRAVITAS-309 trial?

What is the latest update on the GRAVITAS-309 trial?

In this interview, Zeiser presents the initial results from ASH abstract #771: ‘Itacitinib and Corticosteroids As initial Treatment for Chronic Graft-Versus-Host Disease: Phase 1/2 Results from Gravtias-309.’

Firstly, Zeiser discusses how the anti-inflammatory properties of itacitinib as a JAK 1 inhibitor may be beneficial in chronic GvHD. He goes on to outline the overall efficacy and safety of itacitinib in combination with corticosteroids.

More about...
ASH 2022Chronic graft-versus-host diseaseGRAVITAS-309Itacitinib

Related articles

Add bookmark

Itacitinib and corticosteroids for chronic GvHD

During the 64th American Society of Hematology (ASH) Annual Meeting and Exposition, the GvHD Hub was pleased to speak to Annie Im, University of Pittsburgh, Pittsburgh, US. We asked about itacitinib and...

Jan 6, 2023
Add bookmark

Itacitinib and corticosteroids for chronic GvHD

During the 64th American Society of Hematology (ASH) Annual Meeting and Exposition, the GvHD Hub was pleased to speak to Annie Im, University of...

Jan 6, 2023
Add bookmark

Editorial theme | Latest updates on cGvHD treatment

First-line treatment for chronic graft-versus-host disease (cGvHD), which consists of steroids, has not changed much over the last three decades. In the case of severe cGvHD, another...

Apr 19, 2021
Add bookmark

Editorial theme | Latest updates on cGvHD treatment

First-line treatment for chronic graft-versus-host disease (cGvHD), which consists of steroids, has not changed much over the last three decades. In...

Apr 19, 2021

Newsletter

Subscribe to get the best content related to GvHD delivered to your inbox