All content on this site is intended for healthcare professionals only. By acknowledging this message and accessing the information on this website you are confirming that you are a Healthcare Professional.
Introducing
Now you can personalise
your GvHD Hub experience!
Bookmark content to read later
Select your specific areas of interest
View content recommended for you
Find out moreThe GvHD Hub website uses a third-party service provided by Google that dynamically translates web content. Translations are machine generated, so may not be an exact or complete translation, and the GvHD Hub cannot guarantee the accuracy of translated content. The GvHD Hub and its employees will not be liable for any direct, indirect, or consequential damages (even if foreseeable) resulting from use of the Google Translate feature. For further support with Google Translate, visit Google Translate Help.
Bookmark this article
On 21 February 2019, Jacqueline W. Mays from the National Institutes of Health, Bethesda, MD, USA, presented results on behalf of colleagues of a study evaluating whole saliva for the presence of a diagnostic biomarker profile at first onset of oral chronic graft-versus-host disease (cGvHD) prior to initiation of topical steroid therapy at the 2019 TCT Transplantation and Cellular Therapy Meetings of ASBMT and CIBMTR in Houston, Texas, USA.
Jacqueline W. Mays concluded that ZG16B is present in lower amounts in unstimulated whole saliva and within the salivary gland acinar units at oral cGvHD onset. Reduction in the ZG16B protein may indicate cGvHD activity as well as potentially causing salivary gland damage. Dr. Mays added that further investigation in a larger cohort is required to assess whether saliva can be used to identify a diagnostic biomarker profile for oral cGvHD.
Subscribe to get the best content related to GvHD delivered to your inbox