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The GvHD Hub is pleased to present a visual abstract summarizing key findings from a retrospective analysis comparing graft-versus-host disease cyclophosphamide-based prophylaxis posttransplant with sirolimus vs tacrolimus in adult patients undergoing haploidentical allogeneic hematopoietic cell transplantation.1 Most patients were diagnosed with acute myeloid leukemia and a higher proportion of patients in the sirolimus cohort were aged >60 years.
The retrospective study was recently published by Elmariah et al.1 in Transplantation and Cellular Therapy.
To download this visual abstract, click below.Download here
The use of PTCy as GvHD prophylaxis in patients treated with checkpoint inhibitors prior to allo-HCT improves outcomes
Juan Nieto and Betül Oran have each published studies on PTCy as GvHD prophylaxis in patients treated with checkpoint inhibitors...
BMT CTN 1501: Sirolimus versus prednisone for initial treatment of acute GvHD
This article summarizes the final results from the BMT CTN 1501 trial comparing sirolimus to prednisone for the initial treatment of aGvHD.
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