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TypesTherapeuticsCongressesTrialsExpert OpinionsDRUG UPDATES
2024-01-18T16:10:28.000Z

Sirolimus vs tacrolimus in GvHD prophylaxis following haploidentical allo-HCT: a retrospective analysis

By Sheetal Bhurke
Jan 18, 2024
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Learning objective: After reading this article, learners will be able to cite a new clinical development in GvHD prophylaxis.

The GvHD Hub is pleased to present a visual abstract summarizing key findings from a retrospective analysis comparing graft-versus-host disease cyclophosphamide-based prophylaxis posttransplant with sirolimus vs tacrolimus in adult patients undergoing haploidentical allogeneic hematopoietic cell transplantation.1 Most patients were diagnosed with acute myeloid leukemia and a higher proportion of patients in the sirolimus cohort were aged >60 years.

The retrospective study was recently published by Elmariah et al.1 in Transplantation and Cellular Therapy.


Visual Abstract

To download this visual abstract, click below.

Download here

  1. Elmariah H, Otoukesh S, Kumar A, et al. Sirolimus is an acceptable alternative to tacrolimus for graft-versus-host disease prophylaxis after haploidentical peripheral blood stem cell transplantation with post-transplantation cyclophosphamide. Transplant Cell Ther. 2023. Online ahead of print. DOI: 1016/j.jtct.2023.11.010

More about...
Graft-versus-host diseaseSirolimus

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