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Is the novel JAK/ROCK inhibitor TQ05105 effective for patients with SR/SD cGvHD?
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During the European Hematology Association (EHA) 2023 Hybrid Congress, the GvHD Hub was pleased to speak with Yanmin Zhao, Zhejiang University, Hangzhou, CN. We asked, Is the novel JAK/ROCK inhibitor TQ05105 effective for patients with steroid refractory and steroid dependent chronic graft-versus-host disease?
Is the novel JAK/ROCK inhibitor TQ05105 effective for patients with SR/SD cGvHD?
Zhao begins by providing a brief overview of the phase Ib/II trial of TQ05105 in patients with steroid refractory or steroid dependent chronic graft-versus-host disease (NCT04944043). With a best overall response rate of around 87% and a 6-month overall response rate of nearly 60%, she believes that TQ05105 may provide a new treatment option for these patients.
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