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How might itacitinib prophylaxis impact haplo-HSCT outcomes in the future?

During the 63rd ASH Annual Meeting and Exposition, the GvHD Hub was pleased to speak to Ramzi Abboud, Washington University School of Medicine, St. Louis, US. We asked, how might itacitinib prophylaxis impact haploidentical hematopoietic stem cell transplantation (haplo-HSCT) outcomes in the future?

How might itacitinib prophylaxis impact haplo-HSCT outcomes in the future?

In this video, Abboud discusses the role of JAK inhibitors (including itacitinib and ruxolitinib) in the haplo-HSCT setting. He also discusses a pilot study, which him and his team conducted at Washington University School of Medicine, investigating itacitinib in the haplo-HSCT setting (NCT03755414).