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The GvHD Hub are proud to present expert interviews directly from the 61st American Society of Hematology (ASH) meeting in Orlando, US. This interview with Arnon Nagler, Tel Aviv University, Tel Aviv, IL, was based on the question: How do you select the optimal donor for transplant?
Professor Nagler discusses the difficulties that can be faced in finding a matched donor, and notes that haploidentical transplant from a parent, sibling or child is more prominent but less successful. However, new technology, especially non-T-cell depleted transplant with GvHD prophylaxis now can yield good results with almost no difference observed between matched-unrelated and haploidentical donors.
Professor Nagler concludes that sibling donors are the optimal donor where possible, though if there is insufficient time to search for an unrelated donor, then non-T-cell depleted haploidentical transplant with post-transplant cyclophosphamide should be conducted.
How do you select the optimal donor for transplant?
What is new in haploidentical stem cell transplantation?
During the 2021 Transplantation and Cellular Therapy (TCT) Meetings Digital Experience, the GvHD Hub spoke to Arnon Nagler, Tel Aviv University, Tel Aviv, IL. We asked, What is new in...
Monthly theme | GvHD prophylaxis
This article provides an insight into the current standard of care (SOC) regimens for GvHD prophylaxis, therapies under investigation, and expert interviews on the topic.
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