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Does using haplo-HSCT compared with cord blood transplant impact GvHD rates?

Nov 10, 2022
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Learning objective: After reading this article, learners will be able to cite a new clinical development in GvHD.

The GvHD Hub was pleased to speak to Takanori Teshima, Hokkaido University, Sapporo, JP. We asked, Does using haploidentical hematopoietic stem cell transplantation (haplo-HSCT) compared with cord blood transplant impact graft-versus-host disease (GvHD) rates?

Does using haplo-HSCT compared with cord blood transplant impact GvHD rates?

Teshima begins by remarking on the increasing numbers of both haplo-HSCT and cord blood transplants in Japan. Teshima then discusses recent research that has compared haplo-HSCT and cord blood transplant outcomes in terms of acute GvHD and chronic GvHD development, as well as relapse rates, overall survival, and time taken to return to everyday life.

Teshima concludes by commenting on how a patient's risk status may determine the most appropriate treatment option.