ASH 2018 | Practice changing abstracts in graft-versus-host disease 

#601: Results from REACH1, a single-arm phase II study of ruxolitinib in combination with corticosteroids for the treatment of steroid-refractory acute graft-vs-host disease

http://www.gvhdhub.com/medical-information/ash-2018-ruxolitinib-plus-corticosteroids-in-patients-with-steroid-refractory-acute-graft-versus-host-disease-the-reach1-trial

#602: KD025-208: A phase IIa study of KD025 for patients with chronic graft versus host disease (cGVHD) - pharmacodynamics and updated results

http://www.gvhdhub.com/medical-information/ash-2018-pharmacodynamics-and-updated-data-from-the-phase-iia-kd025-208-trial

#605: A phase Ib study of intravenous vedolizumab plus standard of care for graft-versus-host disease prophylaxis in subjects undergoing allogeneic hematopoietic stem cell transplantation for hematologic malignancies: 6-month results

http://www.gvhdhub.com/medical-information/ash-2018-vedolizumab-plus-standard-of-care-to-prevent-graft-versus-host-disease-a-phase-ib-study

#603: Children and adults with steroid-refractory acute graft-versus-host disease respond to treatment with the mesenchymal stromal cell preparation "MSC-Ffm": treatment results for 92 consecutive patients

http://www.gvhdhub.com/medical-information/ash-2018-msc-ffm-for-the-treatment-of-pediatric-and-adult-patients-with-steroid-refractory-graft-versus-host-disease

#69: Metabolomics profiling after allogeneic hematopoietic stem cell transplantation unravels a specific signature in human acute GvHD

http://www.gvhdhub.com/medical-information/ash-2018-the-role-of-metabolomics-profiling-in-acute-graft-versus-host-disease

#359: Pre-transplant and peri-d100 gastrointestinal dysbiosis is associated with the subsequent development of chronic graft-versus-host disease

http://www.gvhdhub.com/medical-information/kate-a-markey-ash-2018-pre-transplant-and-peri-d100-gastrointestinal-dysbiosis-in-chronic-gvhd

#357: Genetic risk of severe chronic graft-versus-host disease defined by host-derived CXCR3 ligands

https://gvhdhub.com/medical-information/prediction-of-severe-chronic-graft-versus-host-disease-by-host-derived-cxcr3-ligand-genes

#356: Serial biomarker monitoring early after HCT identifies different risks for relapse and graft-vs-host disease

https://gvhdhub.com/medical-information/james-ferrara-ash-2018-how-biology-drives-acute-gvhd-biomarkers