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How can Day 100 transcriptomics help to predict development of chronic GvHD?

Featured:

Ben WatkinsBen Watkins

Mar 2, 2021


During the 2021 TCT Meetings Digital Experience, the GvHD Hub spoke to Ben Watkins, Emory University, Atlanta, US. We asked, How can Day 100 transcriptomics help to predict development of chronic GvHD?

How can Day 100 transcriptomics help to predict development of chronic GvHD?

Watkins discusses a model analyzing CD4 T-cell transcriptomics at Day 100 in patients who develop de novo chronic GvHD versus patients displaying operational immune tolerance. Day 100 represented the optimal timepoint to study, as this is often the inflection point between acute and chronic GvHD.